• Endothelial function after pancreas transplantation - A single-center observational study 

      Nordheim, Espen; Dahle, Dag Olav; Strøm Halden, Thea Anine; Birkeland, Kåre I.; Åsberg, Anders; Hartmann, Anders; Horneland, Rune; Jenssen, Trond Geir (Journal article; Tidsskriftartikkel; Peer reviewed, 2020-02-06)
      <i>Background</i> - Patients with diabetes mellitus treated with successful pancreas transplantation (PTX) normalize hyperglycemia, but are exposed to immunosuppressive drugs that may impair endothelial function. This study aimed to evaluate endothelial function in single PTX recipients.<p><p> <i>Methods</i> - Flow‐mediated dilatation (FMD) in the brachial artery was measured by ultrasound 8 weeks ...
    • Evaluation of hypoglycaemia with non-invasive sensors in people with type 1 diabetes and impaired awareness of hypoglycaemia 

      Elvebakk, Ole; Tronstad, Christian; Birkeland, Kåre I.; Jenssen, Trond Geir; Bjørgaas, Marit Ragnhild Rokne; Frøslie, Kathrine Frey; Godang, Kristin; Kalvøy, Håvard; Martinsen, Ørjan Grøttem; Gulseth, Hanne Løvdal (Journal article; Tidsskriftartikkel; Peer reviewed, 2018-10-03)
      People with type 1 diabetes and impaired awareness of hypoglycaemia (IAH) are prone to severe hypoglycaemia. Previous attempts to develop non-invasive hypoglycaemia alarm systems have shown promising results, but it is not known if such alarms can detect severe hypoglycaemia in people with IAH. We aimed to explore whether a combination of non-invasive sensors could reliably evaluate hypoglycaemia ...
    • A multiparameter model for non-invasive detection of hypoglycemia 

      Elvebakk, Ole; Tronstad, Christian; Birkeland, Kåre I.; Jenssen, Trond Geir; Bjørgaas, Marit Ragnhild Rokne; Gulseth, Hanne Løvdal; Kalvøy, Håvard; Høgetveit, Jan Olav; Martinsen, Ørjan Grøttem (Journal article; Tidsskriftartikkel; Peer reviewed, 2019-09-02)
      <i>Objective</i>: Severe hypoglycemia is the most serious acute complication for people with type 1 diabetes (T1D). Approximately 25% of people with T1D have impaired ability to recognize impending hypoglycemia, and nocturnal episodes are feared.<p> <p><i>Approach</i>: We have investigated the use of non-invasive sensors for detection of hypoglycemia based on a mathematical model which combines ...
    • No increase in new users of blood glucose-lowering drugs in Norway 2006-2011: a nationwide prescription database study 

      Strøm, Hanne; Selmer, Randi; Birkeland, Kåre I.; Schirmer, Henrik; Berg, Tore Julsrud; Jenum, Anne Karen; Midthjell, Kristian; Berg, Christian; Stene, Lars Christian (Journal article; Tidsskriftartikkel; Peer reviewed, 2014)
      Background: National estimates for the occurrence of diabetes are difficult to obtain, particularly time trends in incidence. The aim was to describe time trends in prevalent and incident use of blood glucose-lowering drugs by age group and gender in Norway during 2005–2011. Methods: Data were obtained from the nationwide Norwegian Prescription Database. We defined prevalent users of “insulins ...
    • Patient selection for islet or solid organ pancreas transplantation: experiences from a multidisciplinary outpatient-clinic approach 

      Nordheim, Espen; Lindahl, Jørn Petter Hanto; Carlsen, Rasmus Kirkeskov; Åsberg, Anders; Birkeland, Kåre I.; Horneland, Rune; Boye, Birgitte; Scholz, Hanne; Jenssen, Trond Geir (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-02)
      Objective - β-cell replacement therapy (βCRT), including pancreas transplantation alone (PTA) and islet transplantation (ITX), is a treatment option for selected type 1 diabetes patients. All potential candidates for βCRT in Norway are referred to one national transplant centre for evaluation before any pre-transplant workup is started. This evaluation was performed by a transplant nephrologist alone ...